Maintenance treatment of pernicious anaemia by massive parenteral doses of vitamin B12 at intervals of twelve weeks.
نویسنده
چکیده
منابع مشابه
Vitamin B12 deficiency in the elderly: is it worth screening?
Vitamin B12 deficiency is common among the elderly. Elderly people are particularly at risk of vitamin B12 deficiency because of the high prevalence of atrophic gastritis-associated food-cobalamin (vitamin B12) malabsorption, and the increasing prevalence of pernicious anaemia with advancing age. The deficiency most often goes unrecognised because the clinical manifestations are highly variable...
متن کاملVitamin B 12 absorption studies : effect of parenteral non - radioactive vitamin B 12 on serum level of 57 Co vitamin B 12 LILIAN
mean radioactivity in the serum was lower in both patients with pernicious anaemia and in control subjects, and the results in the patients with pernicious anaemia were more definitive. There was no significant difference between the results obtained with an Ekco scaler and those with an I.D.L. scaler. This is the simplest and most convenient method of measuring vitamin B12 absorption. It is su...
متن کاملVitamin B12 Deficiency: Causes, Evaluation and Treatment
Vitamin B12 (cobalamin) deficiency is a major public health problem, particularly among the elderly population. It is known that a deficiency in serum B12 levels can cause a combination of neurological and psychiatric disorders. Therefore, in these cases successful replacement of depleted B12 levels is a necessity. Identification of B12 deficiency in elderly patients can be rather difficult as ...
متن کاملVitamin B12 allergy and successful desensitisation with cyanocobalamin: a case report.
Vitamin B12, as it is not biosynthesised without certain bacteria and algae must be taken with a diet. The most important natural source of vitamin B12 is animal products and deficiency of vitamin B12 most commonly appears as pernicious anaemia. However vitamin B12 deficiency is not only associated with pernicious anaemia but is also linked with neurological conditions. Therefore, patients with...
متن کاملParenteral vitamin B12 reduces hyperhomocysteinemia in end-stage renal disease.
OBJECTIVE The authors found considerably lower plasma total homocysteine (tHcy) concentrations in patients with end-stage renal disease (ESRD) on maintenance hemodialysis, who routinely received high-dose parenteral vitamin B12, than in comparable patients receiving much higher doses of folic acid but only replacement-dose oral vitamin B12. They therefore sought prospective evidence that high-d...
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عنوان ژورنال:
- British medical journal
دوره 1 5166 شماره
صفحات -
تاریخ انتشار 1960